Ascending to higher altitudes causes tightness of the chest because of the expansion of gases in the body cavities and their pressure on the lungs. When man is exposed to low atmospheric pressure at high altitude several symptoms occur as a result of the expansion of gases in the human body. Gases confined in the body cavities such as the stomach, when expanding press on the lungs, which cause breathing difficulty, disturbances, and tightness of the chest. This is like what happens to air passengers when the pressure adjustment system fails inside the airplane.

It has been proven by aeronautics that when man is exposed to high altitude; he suffers from some physiological symptoms that would vary between feeling tightness in his chest and getting into a critical stage if he continues being exposed to high altitude and low atmospheric pressure.

This fact has been stated in Quran as: "Those whom Allah(God) wills to guide, He opens their breast to Islam; those whom He wills to leave straying, He makes their breast close and constricted, as if they had to climb up to the skies: thus Allah(God) heap the penalty on those who refuse to believe." ( Quran : 6 / 125 )

Therefore, we can conclude that the statement "He makes their breast close and constricted, as if they had to climb up to the skies" refers to this physical fact that air pressure decreases in high altitudes and causes tightness of the chest making the breathing hard.

This is another fact that the Quran revealed 1400 years ago.

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